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This means Ligandrol works in a similar way to testosterone and anabolic steroids, although SARMs typically have fewer side effectsthan steroid-type medications. Ligandrol has been a candidate for FDA approval for use in males between 18 and 55 years of age. "We're optimistic that we can get it approved, especially in this age group," says Schoeller. So how does Ligandrol work? The first thing someone will notice if they take Ligandrol is an intense increase in muscle mass. However, unlike anabolic steroids and testosterone, Ligandrol does not bind to the same protein found in testosterone and anabolic steroids, a common problem with SARMs. In contrast, SARMs bind to testosterone and can make it even stronger. The reason why SARMs don't bind to the same protein as LH, LHR, and FSH have already been explained. What is less understood, however, is why SARMs are more effective than the other medications that increase a male's body temperature and testosterone levels. The second thing you will notice is an effect on your sex drive. When you take Ligandrol, your heart rate slows down and your sex drive may increase. In other words, when you take Ligandrol, you're burning more calories. It is also believed that testosterone is transported to the genitals and brain more efficiently when taken with Ligandrol, so it can stimulate the hypothalamus to produce testosterone in men. The third thing you will notice is an increase in confidence. A study by the Department of Psychiatry at the University of Rochester found that men taking 1,300 mg of Ligandrol experienced a 25-42% improvement in their overall health during a 15-day weight loss program. A 2012 study found that men given one tablet of Ligandrol had 40% fewer mood disorders than men given placebo. Schoeller said another interesting aspect of SARMs is that they have the ability to treat men with the condition of polycystic ovarian syndrome, one of the major causes of infertility. "People are starting to recognize the potential of these medications to help alleviate the disease," he said. So far, many researchers are looking into the potential for SARMs to improve certain conditions, including those with Parkinson's disease and severe depression. But as with any new treatment, there is no guarantee these drugs will benefit everyone. "There's always a chance it will not work, that it won't work well," said Schoeller. "That's why we look to see if we can Similar articles: